YF-2

YF-2

CAT N°: 31230
Price:

From 74.00 62.90

YF-2 is a histone acetyltransferase (HAT) activator.{53930} It inhibits proliferation of CCRF-CEM, Hs 578T, A549, and U251 cancer cells (IC50s = 88.7-286 µM), as well as multidrug-resistant NCI/ADR-RES cells (IC50 = 44.8 µM). YF-2 (5 mg/kg) increases reduced acetylated histone H3 levels in a mouse of model of Alzheimer’s disease induced by amyloid-? (1-42) (A?42; Item No. 20574). YF-2 (20 mg/kg) reduces contextual fear memory deficits in the transgenic APP/PS1 mouse model of Alzheimer’s disease.

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