AC-265347

AC-265347

CAT N°: 30937
Price:

48.00 40.80

AC-265347 is a calcimimetic and positive allosteric modulator of the calcium-sensing receptor (CaSR; EC50 = 7.94 nM in a cell-based phosphatidylinositol hydrolysis assay in the presence of calcium).{26279},{54233} It inhibits the proliferation of NIH3T3 cells expressing human CaSR (EC50 = 25.12 nM).{26279} AC-265347 reduces plasma parathyroid hormone levels in rats (ED50 = 0.01 mg/kg).

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