Chrodrimanin B

Chrodrimanin B

CAT N°: 27585
Price:

322.00 273.70

Chrodrimanin B is a meroterpenoid fungal metabolite that has been found in Talaromyces species.{48232} It has insecticidal activity against third instar silkworm larvae (LD50 = 10 ?g/g of diet). Chrodrimanin B selectively inhibits the silkworm GABA receptor RDL (IC50 = 1.13 nM) over human ?1?2?2 subunit-containing GABA receptors (IC50 = 1.48 ?M).{48233} The structure of thailandolide B, originally described as a C-9 epimer of chrodrimanin B, was revised in 2012 and is identical to that of chrodrimanin B.{48232}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • (1R,2R,7aR,8S,9aR,13aS,13bS)-1-(acetyloxy)-1,8,9,9a,10,13a,13b,14-octahydro-5,8-dihydroxy-2,7a,10,10,13a-pentamethyl-2H,4H-benzo[a]pyrano[3,4-j]xanthene-4,11(7aH)-dione
  • Correlated keywords
    • 944726-62-9 Thailandolide ?1 ?2 ?2 C9
  • Product Overview:
    Chrodrimanin B is a meroterpenoid fungal metabolite that has been found in Talaromyces species.{48232} It has insecticidal activity against third instar silkworm larvae (LD50 = 10 ?g/g of diet). Chrodrimanin B selectively inhibits the silkworm GABA receptor RDL (IC50 = 1.13 nM) over human ?1?2?2 subunit-containing GABA receptors (IC50 = 1.48 ?M).{48233} The structure of thailandolide B, originally described as a C-9 epimer of chrodrimanin B, was revised in 2012 and is identical to that of chrodrimanin B.{48232}

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