C-171

C-171

CAT N°: 30159
Price:

From 85.00 72.25

C-171 is an inhibitor of stimulator of interferon genes (STING).{35390,50925} It binds to STING, inhibits its palmitoylation, and prevents the recruitment and phosphorylation of TBK1.{35390} It selectively reduces human and mouse STING-, but not RIG-I or TBK1-, mediated IFN-? reporter activity in HEK293 cells when used at concentrations ranging from 0.02 to 2 ?M.

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • N-(4-hexylphenyl)-5-nitro-2-furancarboxamide
  • Correlated keywords
    • C171 TBK 1 RIGI IFN? HEK 293
  • Product Overview:
    C-171 is an inhibitor of stimulator of interferon genes (STING).{35390,50925} It binds to STING, inhibits its palmitoylation, and prevents the recruitment and phosphorylation of TBK1.{35390} It selectively reduces human and mouse STING-, but not RIG-I or TBK1-, mediated IFN-? reporter activity in HEK293 cells when used at concentrations ranging from 0.02 to 2 ?M.

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