24(S),25-epoxy Cholesterol
24(S),25-epoxy Cholesterol
24(S),25-epoxy Cholesterol is an oxysterol and the most abundant oxysterol in mouse ventral midbrain.{43943} It activates liver X receptors (LXRs)...
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€92.00 €78.20
Neotuberostemonine is an alkaloid originally isolated from S. tuberosa that has diverse biological activities.{55083,55084,55085} It inhibits LPS-induced increases in inducible nitric oxide synthase (iNOS) protein levels and NO production in RAW 264.7 cells when used at a concentration of 100 µM.{55083} Neotuberostemonine (50 µM) inhibits RANKL-induced osteoclast differentiation of RAW 264.7 cells.{55084} It reduces the citric acid-induced cough reflex in conscious guinea pigs when administered at a dose of 133 µmol/kg.{55085} Neotuberostemonine (40 mg/kg) inhibits pulmonary collagen deposition and fibrosis, as well as bronchoalveolar lavage fluid (BALF) monocyte and lymphocyte infiltration in a mouse model of bleomycin-induced pulmonary fibrosis.{55083}
Territorial Availability: Available through Bertin Technologies only in France
| Size | 1 mg, 10 mg, 5 mg |
|---|---|
| Shipping | dry ice |
| CAS number | 143120-46-1 |
| Molecular formula | C22H33NO4 |
| Smiles | O=C(O1)[C@@H](C)[C@]2([H])[C@@]1([H])[C@H](CC)[C@]3([H])[C@]4([H])[C@@]2([H])C[C@]([C@@]5([H])OC([C@@H](C)C5)=O)([H])N4CCCC3 |
| Molecular weight | 375,5 |
| Custom code | 2932.20 |
| Formulation | A crystalline solid |
| Purity | ≥95% |
| UNSPSC code | 12352100 |
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