Deltorphin C (trifluoro<wbr/>acetate salt)

Deltorphin C (trifluoroacetate salt)

CAT N°: 30050
Price:

From 48.00 40.80

Deltorphin C is a peptide agonist of ?-opioid receptors (Ki = 0.15 nM) that has been found in Phyllomedusa bicolor.{46876} It is selective for ?-opioid receptors over µ- and ?-opioid receptors. It induces ?-opioid receptor translocation from large dense-core vesicles to the cell surface and induces calcitonin gene-related peptide (CGRP) release in isolated mouse dorsal root ganglion (DRG) cells when used at concentrations of 0.1 and 1 µM, respectively, effects that can be blocked with the ?-opioid receptor antagonist naltrindole (Item No. 9000705).{46877} Intrathecal administration of deltorphin C (0.15, 1.5, and 15 µg/animal) increases latency to withdraw in the paw pressure and tail-flick tests in rats.{46878}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • L-tyrosyl-D-alanyl-L-phenylalanyl-L-?-aspartyl-L-valyl-L-valyl-glycinamide, trifluoroacetate salt
  • Correlated keywords
    • 122752-15-2 TFA
  • Product Overview:
    Deltorphin C is a peptide agonist of ?-opioid receptors (Ki = 0.15 nM) that has been found in Phyllomedusa bicolor.{46876} It is selective for ?-opioid receptors over µ- and ?-opioid receptors. It induces ?-opioid receptor translocation from large dense-core vesicles to the cell surface and induces calcitonin gene-related peptide (CGRP) release in isolated mouse dorsal root ganglion (DRG) cells when used at concentrations of 0.1 and 1 µM, respectively, effects that can be blocked with the ?-opioid receptor antagonist naltrindole (Item No. 9000705).{46877} Intrathecal administration of deltorphin C (0.15, 1.5, and 15 µg/animal) increases latency to withdraw in the paw pressure and tail-flick tests in rats.{46878}

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