Cyclosporin C

Cyclosporin C

CAT N°: 29152
Price:

From 51.00 43.35

Cyclosporin C is a fungal metabolite that has been found in T. inflatum and has diverse biological activities, including antifungal, antiviral, and immunosuppressant properties.{24990,53111,53112,53113} It is active against isolates of B. cinerea, A. niger, and Alternaria, Mucor, and Penicillium species (MICs = 0.1-5 ?g/ml).{53111} Cyclosporin C (15 ?g/ml) inhibits vaccinia virus replication in infected BSC40 cells by 98.82%.{53112} It inhibits lymphocyte proliferation induced by the mitogens concanavalin A (ConA; Item No. 14951), phytohemagglutinin L (PHA), and pokeweed mitogen (PWM), as well as proliferation induced by alloantigen in mixed lymphocyte culture when used at a concentration of 100 ng/ml.{53113} Cyclosporin C (100 ng/ml) inhibits the local graft versus host (GVH) reaction in mice receiving splenocyte grafts.

We also advise you