5,7-Dihydroxy<wbr/>chromone

5,7-Dihydroxychromone

CAT N°: 29006
Price:

66.00 56.10

5,7-Dihydroxychromone is a flavone decomposition product that has been found in A. hypogaea and has diverse biological activities, including antimicrobial, antioxidant, and neuroprotective properties.{48623,48624} It reduces radial growth of the soil pathogenic fungi R. solani and S. rolfsii (IC50s = 18 and 26 µM, respectively) but has no effect on soil pathogenic bacteria of the genus Bradyrhizobium.{48623} 5,7-Dihydroxychromone (0.4, 2, and 10 µM) reduces increases in apoptosis and the levels of reactive oxygen species (ROS) induced by 6-OHDA (Item No. 25330) in SH-SY5Y neuroblastoma cells. It also increases the levels of HO-1, NQO1, and GCLc in SH-SY5Y cells when used at concentrations ranging from 0.08 to 10 µM.{48624}

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