OUL35

OUL35

CAT N°: 28845
Price:

From 129.00 109.65

OUL35 is an inhibitor of poly(ADP-ribose) polymerase 10 (PARP10; IC50 = 329 nM).{45541} It is selective for PARP10 over a panel of 15 PARP enzymes, including PARP4, PARP14, and PARP16 (IC50s = 22.6, 23.4, and 4.17 ?M, respectively). OUL35 (10 ?M) reverses inhibition of HeLa cell proliferation induced by PARP10 overexpression. It sensitizes HeLa cells to hydroxyurea (Item No. 23725), increasing hydroxyurea-induced inhibition of cell proliferation when used at a concentration of 5 ?M.

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 4,4?-oxybis-benzamide
  • Correlated keywords
    • oxydi 4-(4-Carbamoylphenoxyl)benzamide Carbamoylphenoxy OUL-35 NSC39047 PARP-10 PARP-4 PARP-14 PARP-16 hydroxy-urea
  • Product Overview:
    OUL35 is an inhibitor of poly(ADP-ribose) polymerase 10 (PARP10; IC50 = 329 nM).{45541} It is selective for PARP10 over a panel of 15 PARP enzymes, including PARP4, PARP14, and PARP16 (IC50s = 22.6, 23.4, and 4.17 ?M, respectively). OUL35 (10 ?M) reverses inhibition of HeLa cell proliferation induced by PARP10 overexpression. It sensitizes HeLa cells to hydroxyurea (Item No. 23725), increasing hydroxyurea-induced inhibition of cell proliferation when used at a concentration of 5 ?M.

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