14S(15R)-EET

14S(15R)-EET

CAT N°: 28631
Price:

From 182.00 154.70

14S(15R)-EET is an oxylipin and a cytochrome P450 metabolite of arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607).{52397} 14S(15R)-EET binds to isolated guinea pig monocytes with a Ki value of 612.5 nM in a competitive binding assay using [3H]14(15)-EET.{52398} It induces dilation of precontracted isolated canine epicardial arterioles (EC50 = 4 pM) and denuded porcine subepicardial arterioles (EC50 = 3 pM).{52399} Unlike 14R(15S)-EET, 14S(15R)-EET does not inhibit COX in enzyme assays or isolated platelets.{642}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • (5Z,8Z,11Z)-13-[(2S,3R)-3-pentyl-2-oxiranyl]-5,8,11-tridecatrienoic acid
  • Correlated keywords
    • P-450 81276-03-1
  • Product Overview:
    14S(15R)-EET is an oxylipin and a cytochrome P450 metabolite of arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607).{52397} 14S(15R)-EET binds to isolated guinea pig monocytes with a Ki value of 612.5 nM in a competitive binding assay using [3H]14(15)-EET.{52398} It induces dilation of precontracted isolated canine epicardial arterioles (EC50 = 4 pM) and denuded porcine subepicardial arterioles (EC50 = 3 pM).{52399} Unlike 14R(15S)-EET, 14S(15R)-EET does not inhibit COX in enzyme assays or isolated platelets.{642}

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