10-deacetyl Paclitaxel

10-deacetyl Paclitaxel

CAT N°: 28503
Price:

From 74.00 62.90

10-deacetyl Paclitaxel (10-DAP) is a taxane and precursor in the semisynthetic synthesis of paclitaxel (Item No. 10461) that has been found in Taxus and has anticancer activity.{47706,47707} It is cytotoxic to KB carcinoma cells (EC50 = 0.027 ?g/ml).{47706} 10-DAP (16 mg/kg) reduces tumor growth in the PS mouse lymphocytic leukemia model.

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • (?R,?S)-?-(benzoylamino)-?-hydroxy-benzenepropanoic acid, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester
  • Correlated keywords
    • 111149-94-1 135501-18-7 176702-78-6 10DAP deacetyl-taxol Desacetylpaclitaxel Desacetyl Deacetylpaclitaxel anti-cancer semi-synthetic cyto-toxic
  • Product Overview:
    10-deacetyl Paclitaxel (10-DAP) is a taxane and precursor in the semisynthetic synthesis of paclitaxel (Item No. 10461) that has been found in Taxus and has anticancer activity.{47706,47707} It is cytotoxic to KB carcinoma cells (EC50 = 0.027 ?g/ml).{47706} 10-DAP (16 mg/kg) reduces tumor growth in the PS mouse lymphocytic leukemia model.

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