Secretin (human) (trifluoro<wbr/>acetate salt)

Secretin (human) (trifluoroacetate salt)

CAT N°: 24990
Price:

385.00 327.25

Secretin is an endogenous 27-amino acid gastrointestinal hormone and neuropeptide that regulates secretion from the stomach, pancreas, and liver.{38733,38734} It belongs to the secretin/glucagon superfamily of peptides, which includes glucagon (Item No. 24204), glucagon-like peptide-1 (GLP-1; Item No. 24460), GLP-2 (Item No. 24414), and pituitary adenylate cyclase-activating polypeptide (PACAP; Item Nos. 24769 | 24770).{36556} Secretin dose-dependently increases somatostatin release from primary human antral cells in vitro.{42019} In vivo, secretin dose-dependently increases the volume of pancreatic secretion as well as inhibits gastric acid secretion induced by gastrin I (Item No. 24457) in rats when administered at a dose of 100 pmol/kg per h.{38736} Secretin (40 ?g/kg, i.v.) increases the number of neurons expressing c-fos in the central amygdala and area postrema in rats.{42020}

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