Sultriecin

Sultriecin

CAT N°: 27976
Price:

402.00 341.70

Sultriecin is a fungal metabolite originally isolated from S. roseiscleroticus.{46276} It is active against a panel of 15 fungal strains (MICs = 0.8-50 ?g/ml). Sultriecin is cytotoxic to B16/F10, HCT116, Moser, P388, A549, and K562 cancer cells (IC50s = 37.7, 1.92, 0.85, 3.8, 4.14, and 0.67 ?g/ml, respectively). It also inhibits RNA and protein synthesis in L1210 leukemia cells (IC50s = 5.5 and 2.4 ?g/ml, respectively). Sultriecin (0.1-10 mg/kg) increases survival time in a B16/F10 syngeneic mouse melanoma model and a P388 murine leukemia model.

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