ADL5859 (hydro<wbr/>chloride)

ADL5859 (hydrochloride)

CAT N°: 27796
Price:

From 293.00 249.05

ADL5859 is a ?-opioid receptor agonist (Ki = 0.84 nM).{45386} It is selective for ?-opioid receptors over ?-opioid and ?-opioid receptors exhibiting 32 and 37% inhibition, respectively, in radioligand binding assays when used at a concentration of 10 ?M. ADL5859 (3 mg/kg) completely reverses mechanical hyperalgesia induced by complete Freund’s adjuvant (CFA) in rats. It also decreases immobility time in the forced swim test in rats, indicating antidepressant-like activity.

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