GNE-317

GNE-317

CAT N°: 27671
Price:

From 91.00 77.35

GNE-317 is a dual inhibitor of PI3K? and the mammalian target of rapamycin (mTOR; apparent Kis = 2 and 9 nM, respectively).{58697} It inhibits the proliferation of PC3 prostate cancer and A172 glioblastoma cells with EC50 values of 132 and 240 nM, respectively. GNE-317 (10-40 mg/kg) reduces tumor growth in a U87MG/M glioblastoma mouse xenograft model.

We also advise you