Globosuxanthone A

Globosuxanthone A

CAT N°: 27486
Price:

From 182.00 154.70

Globosuxanthone A is a fungal metabolite originally isolated from C. globosum.{48211} It is cytotoxic to various human solid tumor cell lines, including MCF-7, PC3, LNCap, and DU145 cells (IC50s = 1.3, 0.65, 1.5, and 1.2 µM, respectively). It induces accumulation of cells in the G2/M and S phases of the cell cycle in NCI-H460 and PC3M cells. Globosuxanthone A is also active against C. albicans but not S. aureus, E. coli, or M. hiemalis.{48212}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • (1R,2R)-2,9-dihydro-1,2,8-trihydroxy-9-oxo-1H-xanthene-1-carboxylic acid, methyl ester
  • Correlated keywords
    • Chaetomium MCF7 PC 3 LN Cap DU 145 NCIH460 H 460 3M candida staphylococcus Escherichia Mucor
  • Product Overview:
    Globosuxanthone A is a fungal metabolite originally isolated from C. globosum.{48211} It is cytotoxic to various human solid tumor cell lines, including MCF-7, PC3, LNCap, and DU145 cells (IC50s = 1.3, 0.65, 1.5, and 1.2 µM, respectively). It induces accumulation of cells in the G2/M and S phases of the cell cycle in NCI-H460 and PC3M cells. Globosuxanthone A is also active against C. albicans but not S. aureus, E. coli, or M. hiemalis.{48212}

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