6-O-desmethyl Donepezil

6-O-desmethyl Donepezil

CAT N°: 27175
Price:

176.00 149.60

6-O-desmethyl Donepezil is an active metabolite of the acetylcholinesterase inhibitor donepezil (Item No. 13245).{42676} It is formed through dealkylation by the cytochrome P450 (CYP) isoform CYP2D6.{42677} It inhibits human ether a go-go (hERG) channels (IC50 = 1.5 µM in HEK293 cells expressing hERG).{42676}

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