Ac-IETD-CHO (trifluoro<wbr/>acetate salt)

Ac-IETD-CHO (trifluoroacetate salt)

CAT N°: 27100
Price:

From 122.00 103.70

Ac-IETD-CHO is an inhibitor of caspase-8 (IC50 = 5 nM).{38794} It inhibits fluticasone propionate-induced increases in apoptosis in peripheral blood T-cells isolated from patients with asthma when used at a concentration 60 ?M.{46116} Ac-IETD-CHO (10 mg/kg) inhibits increases in hepatic caspase-3 activity, DNA fragmentation, cytosolic cytochrome c levels, and proteolytic processing of caspase-3, -8, and -9 proenzymes in a mouse model of Fas-induced apoptosis and liver failure.{46117}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • N-acetyl-L-isoleucyl-L-?-glutamyl-N-[(1S)-2-carboxy-1-formylethyl]-L-threoninamide, trifluoroacetate salt
  • Correlated keywords
    • 844856-14-0 191338-86-0 AcIETDCHO AcIleGluThrAspCHO Acetyl-Ile-Glu-Thr-Asp-aldehyde N-Acetyl-Ile-Glu-Thr-Asp-al AcetylIleGluThrAspaldehyde NAcetylIleGluThrAspal
  • Product Overview:
    Ac-IETD-CHO is an inhibitor of caspase-8 (IC50 = 5 nM).{38794} It inhibits fluticasone propionate-induced increases in apoptosis in peripheral blood T-cells isolated from patients with asthma when used at a concentration 60 ?M.{46116} Ac-IETD-CHO (10 mg/kg) inhibits increases in hepatic caspase-3 activity, DNA fragmentation, cytosolic cytochrome c levels, and proteolytic processing of caspase-3, -8, and -9 proenzymes in a mouse model of Fas-induced apoptosis and liver failure.{46117}

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