β-Apooxytetracycline

β-Apooxytetracycline

CAT N°: 27099
Price:

From 60.00 51.00

?-Apooxytetracycline is a potential impurity found in commercial preparations of oxytetracycline.{43923} ?-Apooxytetracycline is a degradation product formed from oxytetracycline (Item No. 18076) via acid hydrolysis. It has a relative potency of 0.1 compared with oxytetracycline for inhibiting the growth of aerobic sludge bacteria, an MIC50 value of 32 mg/L for tetracycline-sensitive strains of Pseudomonas, and MIC50 values of greater than 32 mg/L for tetracycline-sensitive strains of Agrobacterium, Moraxella, and Bacillus, as well as tetracycline-resistant strains of E. coli.{43924} ?-Apooxytetracycline (10 mg/kg) is toxic to rats, decreasing body weight, disrupting blood cell counts, and inducing hepatocyte necrosis.{43925}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • (3S,4S,5R)-4-[(3R)-1,3-dihydro-4,5-dihydroxy-9-methyl-3-oxonaphtho[2,3-c]furan-1-yl]-3-(dimethylamino)-2,5-dihydroxy-6-oxo-1-cyclohexene-1-carboxamide
  • Correlated keywords
    • 1361013-49-1 AOTC Escherichia oxy tetra cycline Apo-terramycin terra-mycin agro-bacterium
  • Product Overview:
    ?-Apooxytetracycline is a potential impurity found in commercial preparations of oxytetracycline.{43923} ?-Apooxytetracycline is a degradation product formed from oxytetracycline (Item No. 18076) via acid hydrolysis. It has a relative potency of 0.1 compared with oxytetracycline for inhibiting the growth of aerobic sludge bacteria, an MIC50 value of 32 mg/L for tetracycline-sensitive strains of Pseudomonas, and MIC50 values of greater than 32 mg/L for tetracycline-sensitive strains of Agrobacterium, Moraxella, and Bacillus, as well as tetracycline-resistant strains of E. coli.{43924} ?-Apooxytetracycline (10 mg/kg) is toxic to rats, decreasing body weight, disrupting blood cell counts, and inducing hepatocyte necrosis.{43925}

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