GLP-2 (human) (trifluoroacetate salt)

GLP-2 (human) (trifluoroacetate salt)

CAT N°: 24414
Price:

487.00 413.95

Glucagon-like peptide-2 (GLP-2) is an endogenous peptide hormone formed in L cells of the small and large intestine by cleavage of proglucagon in response to nutrient ingestion.{39479,39480} In vivo, GLP-2 (43.75 ?g twice a day) increases crypt cell proliferation, total weight of the small bowel, and mucosal thickness of the proximal and distal jejunum and ileum in mice.{39479} It increases jejunal mucosal surface area and reduces resection-induced decreases in SGLT-1 and GLUT-2 transporter abundance, as well as resection-induced increases in blood glucose levels and body fat loss, in a rat model of distal bowel resection.{39481} GLP-2 also increases intrahepatic lipid concentration, hepatic steatosis, and plasma concentrations of cholesterol and triglycerides in mice fed a high-fat diet but has no effect on mice fed a standard diet.{39480}

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