Ornidazole

Ornidazole

CAT N°: 26818
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From 92.00 78.20

Ornidazole is an orally bioavailable 5-nitroimidazole derivative with antibacterial and antiprotozoal activities.{35717,26702} Ornidazole inhibits the growth of clinical isolates of B. fragilis (MICs = 0.5-5 ?M) and various anaerobic bacteria when used at concentrations ranging from less than 0.1 to 3.2 ?g/ml.{26702,48267} It also inhibits the growth of Giardia isolates (IC50s = 0.01-0.47 ?g/ml).{48268} Oral administration of ornidazole reduces T. vaginalis and T. foetus infection in mice and E. histolytica infection in rats with curative dose (CD50) values of 37, 3, and 10 mg/kg, respectively.{35717} Ornidazole (400 mg/kg per day) induces infertility in male rats within 7 days and inhibits spermatozoa binding to rat oocyte zona pellucida.{48269,48270}

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