Omeprazole sulfone-d<sub>3</sub>

Omeprazole sulfone-d3

CAT N°: 26784
Price:

237.00 201.45

Omeprazole sulfone-d3 is intended for use as an internal standard for the quantification of omeprazole sulfone (Item No. 18882) by GC- or LC-MS. Omeprazole sulfone is the major metabolite of the gastric proton pump inhibitor, omeprazole (Item No. 14880). It is produced by cytochrome P450 (CYP)3A4 sulfoxidation of esomeprazole magnesium (Item No. 17326) and is found in plasma.{30673} Omeprazole sulfone has been shown to act as a reversible direct-acting and metabolism-dependent inhibitor of CYP2C19 in pooled human liver microsomes (IC50 = 18 µM).{30672}

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