Schisantherin B

Schisantherin B

CAT N°: 26716
Price:

92.00 78.20

Schisantherin B (STB) is a lignan originally isolated from S. sphenanthera fruit.{47351} It inhibits formation of advanced glycation end products (AGEs) in vitro.{47352} STB (0.1 mg/kg) decreases escape latency in the Morris water maze and increases spontaneous alternation in the Y-maze in a mouse model of Alzheimer’s disease induced by amyloid-? (1-42) (Item No. 20574).{47353} It increases glial expression of glutamate transporter 1 (GLP-1) and decreases immobility time in the forced swim test (FST) in mice, indicating antidepressant-like activity.{47354} STB also increases spontaneous alternation in the Y-maze in a mouse model of stress-induced short-term learning impairment induced by the FST.

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