Paraherquamide A

Paraherquamide A

CAT N°: 26685
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Paraherquamide A is a mycotoxin anthelmintic originally isolated from P. paraherquei.{47167} It binds to acetylcholine receptors (IC50 = 0.5 nM for head homogenates of M. domestica) and acts as an antagonist.{47167,47168} Paraherquamide A is toxic to C. elegans (LD50 = 2.5 µg/ml) and effective against T. colubriformis infection in gerbils when used at doses ranging from 0.39 to 200 mg/kg.{47169,47170} It is toxic to mice (LD50 = 14.9 mg/kg).{47171}

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