Clarithro<wbr/>mycin-<sup>13</sup>C-d<sub>3</sub>

Clarithromycin-13C-d3

CAT N°: 26678
Price:

182.00 154.70

Clarithromycin-13C-d3 is intended for use as an internal standard for the quantification of clarithromycin (Item No. 19455) by GC- or LC-MS. Clarithromycin is a polyketide synthase-derived semisynthetic macrolide antibiotic.{31455,22680,60822} It is active against methicillin-susceptible, but not methicillin-resistant, S. aureus (MIC50s = 0.06 and >128 µg/ml), S. pyogenes, L. monocytogenes, and B. pertussis (MIC50 = 0.015, 0.25, and ?0.008 µg/ml, respectively), among others.{31455} Clarithromycin (25 mg/kg) decreases the number of colony-forming units (CFUs) in the spleen in a mouse model of M. avium infection.{60823} Formulations containing clarithromycin have been used in the treatment of bacterial infections and, when used in combination with other antibiotics, in the treatment of H. pylori.

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