Netilimicin (sulfate)

Netilimicin (sulfate)

CAT N°: 26666
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From 146.00 124.10

Netilimicin is an aminoglycoside antibiotic.{47386} It is active against S. aureus, N. gonorrhoeae, E. coli, P. mirabilis, and P. aeruginosa (MICs = 0.4, 3.1, 0.8, 1.6, and 0.4 µg/ml, respectively) as well as Enterococci, Enterobacter, Citrobacter, and Klebsiella species (MICs = 3.1, 0.4, 0.8, and ?0.2 µg/ml, respectively). Netilimicin induces nephrotoxicity in rats when administered at doses ranging from 50 to 150 mg/kg.{47387} It also induces neuromuscular block, decreasing twitch tension in isolated diaphragm and soleus muscles in rabbits (ED50s = 18.5 and 62.2 mg/kg, respectively).{47388} Formulations containing netilimicin were previously used in the intravenous treatment of severe bacterial infections.

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