(+)-D-threo–PDMP (hydrochloride)
(+)-D-threo–PDMP (hydrochloride)
(+)-D-threo-PDMP is a ceramide analog and is one of the four possible stereoisomers of PDMP (Item No. 62595).{11392} (+)-D-threo-PDMP is...
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€55.00 €46.75
€55.00 €46.75
Permethrin is a modulator of voltage-gated sodium channels (NaV) that is used as an insecticide.{36375} It delays channel deactivation of the NaV1.8 channel expressed in X. laevis oocytes. It is at least 100-fold more potent at insect than mammalian sodium channels, leading to slow deactivation of D. para/TipE, but not rat brain IIA or ?1, sodium channels expressed in X. laevis oocytes when used at a concentration of 500 nM.{36376} Permethrin (5 µM) increases sodium influx in BV-2 and primary microglial cells by approximately 28 and 29%, respectively, and activates microglia.{36377} Long-term application of permethrin leads to dose- and time-dependent intracellular sodium accumulation and TNF-? release in microglia in vitro. Formulations containing permethrin have been used for the treatment of head lice and scabies infestations.
Territorial Availability: Available through Bertin Technologies only in France
| Size | 100 mg |
|---|---|
| Shipping | dry ice |
| CAS number | 52645-53-1 |
| Molecular formula | C21H20Cl2O3 |
| Smiles | O=C(C1C(C)(C)C1/C=C(Cl)/Cl)OCC2=CC(OC3=CC=CC=C3)=CC=C2 |
| Molecular weight | 391,3 |
| Formulation | A crystalline solid |
| Purity | ≥95% (mixture of isomers) |
| Custom code | 2914.50 |
| UNSPSC code | 12352100 |
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