Cefradine

Cefradine

CAT N°: 26060
Price:

From 49.00 41.65

Cefradine is an orally bioavailable ?-lactam cephalosporin antibiotic.{42982} It is active against S. pyogenes, E. coli, K. pneumoniae, and E. cloacae (MICs = 0.04, 9.4, 9.4, and 6.3 ?g/ml, respectively). Cefradine is also active against clinical isolates of S. aureus (MICs = 0.8-6 ?g/ml) and S. pyogenes (MICs = 0.1-0.4 ?g/ml), as well as H. influenzae, E. coli, and K. pneumoniae (MICs = 6.2-12.5 ?g/ml).{42983} It increases survival in mouse models of systemic lethal infection by S. pyogenes, E. coli, K. pneumoniae, or E. cloacae (ED50s = 5, 37, 122, and 50 mg/kg, respectively), as well as by penicillin-susceptible or -resistant strains of S. aureus (ED50s = 18 and 91 mg/kg, respectively).{42982} Formulations containing cefradine have previously been used in the treatment of respiratory and urinary tract infections, skin infections, and otitis media.

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