Glucosylceramide (plant)

Glucosylceramide (plant)

CAT N°: 25850
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From 166.00 141.10

Glucosylceramides are formed by the tethering of glucose to a ceramide by glucosylceramide synthase.{41133} They are present in neuronal and non-neuronal mammalian tissues and are found at low quantities in a large number of plant species, where they comprise 5-30% of total lipids in the plant plasma membrane, and in fungi.{41133,41134,59454} Glucosylceramides levels decrease during cold acclimatization in plants and glucosylceramides in fungi are involved in the regulation of virulence and act as elicitors in plants, stimulating plant defense mechanisms.{59454,59455} Glucosylceramides are precursors in the synthesis of lactosylceramides and gangliosides. Increased levels of glucosylceramides are associated with obesity-induced insulin resistance in mice and with neuronal deficits observed in neuronopathic Gaucher disease.{41133,41135} This product contains glucosylceramide molecular species with primarily 2-hydroxy C16:0 fatty acyl chain lengths. As this product is derived from a natural source, there may be variations in the sphingoid backbone. [Matreya, LLC. Catalog No. 1522]

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