24(S),25-epoxy Cholesterol
24(S),25-epoxy Cholesterol
24(S),25-epoxy Cholesterol is an oxysterol and the most abundant oxysterol in mouse ventral midbrain.{43943} It activates liver X receptors (LXRs)...
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Latanoprostene bunod is a nitric oxide-donating prostaglandin F2? (FP) receptor agonist that is converted to latanoprost (free acid) (Item No. 16811) and nitric oxide (NO) in vivo.{43936} It induces cGMP accumulation in PC12 and HEK293 cells (EC50s = 1.6 and 9.2 ?M, respectively). Topical administration of latanoprostene bunod (0.036% solution) reduces intraocular pressure (IOP) in canine and rabbit models of glaucoma. It also decreases IOP in a cynomolgus monkey model of laser-induced ocular hypertension.
Territorial Availability: Available through Bertin Technologies only in France
| Size | 1 mg, 10 mg, 5 mg, 500 µg |
|---|---|
| Shipping | dry ice |
| CAS number | 860005-21-6 |
| Molecular formula | C27H41NO8 |
| Smiles | O[C@@H]1[C@H](C/C=CCCCC(OCCCCO[N+]([O-])=O)=O)[C@@H](CC[C@H](CCC2=CC=CC=C2)O)[C@H](O)C1, O[C@@H]1[C@H](C/C=CCCCC(OCCCCO[N+]([O-])=O)=O)[C@@H](CC[C@H](CCC2=CC=CC=C2)O)[C@H](O)C1, O[C@@H]1[C@H](C/C=CCCCC(OCCCCO[N+]([O-])=O)=O)[C@@H](CC[C@H](CCC2=CC=CC=C2)O)[C@H](O)C1, O[C@@H]1[C@H](C/C=CCCCC(OCCCCO[N+]([O-])=O)=O)[C@@H](CC[C@H](CCC2=CC=CC=C2)O)[C@H](O)C1 |
| Molecular weight | 507,6 |
| Custom code | 2937.50 |
| Formulation | A solution in ethanol |
| Purity | ≥95% |
| UNSPSC code | 12352100 |
Cayman Chemical’s mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.
Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.
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