Chelidonine

Chelidonine

CAT N°: 25097
Price:

From 49.00 41.65

Chelidonine is a benzophenanthridine alkaloid that has been isolated from C. majus.{42238,42237} It induces Bcl-2- and caspase-dependent apoptosis in HepG2 human liver carcinoma cells with an LC50 value of 12 µM and in Jurkat human T cells when used at a concentration of 1 µM.{42238,42236} Chelidonine also downregulates hTERT expression in HepG2 cells, reduces telomerase activity, and induces cell senescence.{42238}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 5bR,6S,7,12bS,13,14-hexahydro-13-methyl-[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridin-6-ol
  • Correlated keywords
    • 5907-33-5 10367-14-3 47476-03-9 52503-79-4 855174-41-3 Chelidonin Stylophorine Stylophorin helidonine Bcl2 Hep-G2 Chelidonium hexahydrobenzophenanthridine
  • Product Overview:
    Chelidonine is a benzophenanthridine alkaloid that has been isolated from C. majus.{42238,42237} It induces Bcl-2- and caspase-dependent apoptosis in HepG2 human liver carcinoma cells with an LC50 value of 12 µM and in Jurkat human T cells when used at a concentration of 1 µM.{42238,42236} Chelidonine also downregulates hTERT expression in HepG2 cells, reduces telomerase activity, and induces cell senescence.{42238}

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