24(S),25-epoxy Cholesterol
24(S),25-epoxy Cholesterol
24(S),25-epoxy Cholesterol is an oxysterol and the most abundant oxysterol in mouse ventral midbrain.{43943} It activates liver X receptors (LXRs)...
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Scutellarein is a flavone that has been isolated from S. baicalensis and has antioxidant, enzyme inhibitory, anti-inflammatory, and antiproliferative biological activities.{37603,37604,37605,37606,37607,37608} It has antioxidant activity in a total reactive antioxidant potential (TRAP) assay when used at a concentration of 1 ?g/ml.{37604} Scutellarein inhibits sucrose hydrolysis by rat intestinal ?-glucosidase and ATPase activity of the severe acute respiratory syndrome (SARS) coronavirus helicase nsP13 (IC50s = 12 and 0.86 ?M, respectively).{37605,37606} It decreases nitric oxide (NO) release and mRNA expression of inducible NO synthase (iNOS) and TNF-? induced by LPS in RAW 264.7 macrophages when used at a concentration of 50 ?M.{37607} In vivo, scutellarein (0.5 ?g/g) decreases tumor weight and volume in an HT-1080 human fibrosarcoma mouse xenograft model.{37608}
Territorial Availability: Available through Bertin Technologies only in France
| Size | 1 mg, 10 mg, 5 mg, 50 mg |
|---|---|
| Shipping | dry ice |
| CAS number | 529-53-3 |
| Molecular formula | C15H10O6 |
| Smiles | OC1=C(O)C(O)=C(C(C=C(C2=CC=C(O)C=C2)O3)=O)C3=C1 |
| Molecular weight | 286,2 |
| Custom code | 2907.29 |
| Formulation | A crystalline solid |
| Purity | ≥98% |
| UNSPSC code | 12352100 |
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