Scutellarein

Scutellarein

CAT N°: 24977
Price:

54.00 45.90

Scutellarein is a flavone that has been isolated from S. baicalensis and has antioxidant, enzyme inhibitory, anti-inflammatory, and antiproliferative biological activities.{37603,37604,37605,37606,37607,37608} It has antioxidant activity in a total reactive antioxidant potential (TRAP) assay when used at a concentration of 1 ?g/ml.{37604} Scutellarein inhibits sucrose hydrolysis by rat intestinal ?-glucosidase and ATPase activity of the severe acute respiratory syndrome (SARS) coronavirus helicase nsP13 (IC50s = 12 and 0.86 ?M, respectively).{37605,37606} It decreases nitric oxide (NO) release and mRNA expression of inducible NO synthase (iNOS) and TNF-? induced by LPS in RAW 264.7 macrophages when used at a concentration of 50 ?M.{37607} In vivo, scutellarein (0.5 ?g/g) decreases tumor weight and volume in an HT-1080 human fibrosarcoma mouse xenograft model.{37608}

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