C18 dihydro Ceramide (d18:0/18:0)

C18 dihydro Ceramide (d18:0/18:0)

CAT N°: 24379
Price:

From 140.00 119.00

C18 dihydro Ceramide is a bioactive sphingolipid and precursor in the de novo synthesis of C18 ceramide (Item No. 19556) that lacks the 4,5-trans double bond.{40697} Increased C18 dihydroceramide lipid levels lead to increased triacylglycerol storage and autophagosome accumulation as well as upregulation of the fibrosis markers ?-SMA and FGF2 in Chang and LX-2 liver cells. C18 dihydro Ceramide is elevated in the plasma of pre-diabetics up to 9 years prior to the onset of type 2 diabetes.{40698} It is also elevated in the skin of patients with lesional atopic dermatitis.{40696}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • N-[(1S,2R)-2-hydroxy-1-(hydroxymethyl)heptadecyl]-octadecanamide
  • Correlated keywords
    • TIC 001 TIC001 NS C-18 smooth muscle actin fibroblast growth factor FGF-2
  • Product Overview:
    C18 dihydro Ceramide is a bioactive sphingolipid and precursor in the de novo synthesis of C18 ceramide (Item No. 19556) that lacks the 4,5-trans double bond.{40697} Increased C18 dihydroceramide lipid levels lead to increased triacylglycerol storage and autophagosome accumulation as well as upregulation of the fibrosis markers ?-SMA and FGF2 in Chang and LX-2 liver cells. C18 dihydro Ceramide is elevated in the plasma of pre-diabetics up to 9 years prior to the onset of type 2 diabetes.{40698} It is also elevated in the skin of patients with lesional atopic dermatitis.{40696}

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