24(S),25-epoxy Cholesterol
24(S),25-epoxy Cholesterol
24(S),25-epoxy Cholesterol is an oxysterol and the most abundant oxysterol in mouse ventral midbrain.{43943} It activates liver X receptors (LXRs)...
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p,p’-DDE is a metabolite and degradation product of the organochlorine pesticide DDT.{39801} It accumulates in smallmouth buffalo, channel catfish, and largemouth bass as well as sediment in the Huntsville Spring Branch-Indian Creek tributary system surrounding a DDT manufacturing plant where it is considered a persistent organic pollutant (POP). p,p’-DDE inhibits estrogen binding to rainbow trout estrogen receptors (rtERs) with an IC50 value of 8 µM.{12991} It induces concentration-dependent secretion of estradiol by granulosa and theca cell co-cultures isolated from porcine ovarian follicles.{39802} p,p’-DDE (50-100 µM) also decreases ATP levels, the proportion of sperm with high mitochondrial membrane potential, and motility of human sperm in vitro.{42280}
Territorial Availability: Available through Bertin Technologies only in France
| Size | 100 mg, 50 mg |
|---|---|
| Shipping | dry ice |
| CAS number | 72-55-9 |
| Molecular formula | C14H8Cl4 |
| Smiles | ClC1=CC=C(/C(C2=CC=C(Cl)C=C2)=C(Cl)Cl)C=C1, ClC1=CC=C(/C(C2=CC=C(Cl)C=C2)=C(Cl)Cl)C=C1 |
| Molecular weight | 318 |
| Custom code | 2903.99 |
| Formulation | A solid |
| Purity | ≥98% |
| UNSPSC code | 12352100 |
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Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.
Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.
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Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.
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