Humanin (human) (trifluoro<wbr/>acetate salt)

Humanin (human) (trifluoroacetate salt)

CAT N°: 24150
Price:

From 276.00 234.60

Humanin is a neuroprotective peptide.{41388} It completely blocks amyloid-? (1-42) (A?42) and A?43-induced cell death of primary cortical neurons when used at a concentration of 10 ?M. Humanin also prevents amyloid precursor protein (APP) antibody-induced cell death and reduces neurotoxicity in FH11 cells induced by the APP mutants A617G-APP, L648P-APP, V642I-APP, and NL-APP, which are associated with familial Alzheimer’s disease (IC50s = 0.1-1 ?M). In vivo, humanin (0.375 mg/kg per hour) increases systemic insulin sensitivity and enhances glucose uptake in skeletal muscle of rats.{41389}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • L-methionyl-L-alanyl-L-prolyl-L-arginylglycyl-L-phenylalanyl-L-seryl-L-cysteinyl-L-leucyl-L-leucyl-L-leucyl-L-leucyl-L-threonyl-L-seryl-L-?-glutamyl-L-isoleucyl-L-?-aspartyl-L-leucyl-L-prolyl-L-valyl-L-lysyl-L-arginyl-L-arginyl-L-alanine, trifluoroacetate salt
  • Correlated keywords
    • CG202524-01 PRO86272 neuro-protective toxicity FH-11 A?-42 43 t lymphocyte activation-associated CG 202524-01 20252401 CG20252401 PRO 86272 330936-69-1
  • Product Overview:
    Humanin is a neuroprotective peptide.{41388} It completely blocks amyloid-? (1-42) (A?42) and A?43-induced cell death of primary cortical neurons when used at a concentration of 10 ?M. Humanin also prevents amyloid precursor protein (APP) antibody-induced cell death and reduces neurotoxicity in FH11 cells induced by the APP mutants A617G-APP, L648P-APP, V642I-APP, and NL-APP, which are associated with familial Alzheimer’s disease (IC50s = 0.1-1 ?M). In vivo, humanin (0.375 mg/kg per hour) increases systemic insulin sensitivity and enhances glucose uptake in skeletal muscle of rats.{41389}

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