Isoflurane

Isoflurane

CAT N°: 23989
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From 48.00 40.80

Isoflurane is a halogenated ether with anesthetic properties.{37284} While the mechanism of isoflurane anesthesia is not fully understood, mice resistant to isoflurane anesthesia have an 86% decrease in gene expression for the GABAA receptor subunit ?1 compared with isoflurane-sensitive mice, indicating that the GABAA receptor may be required for its anesthetic effect. In mice, isoflurane (1.5% for 4 hours) impairs spatial recognition memory in the spontaneous alternation test and Y-maze and increases levels of phosphorylated Jnk1/2 for at least 24 hours.{37283} Formulations containing isoflurane have been used as anesthetics.

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