Cefamandole Nafate

Cefamandole Nafate

CAT N°: 23988
Price:

From 83.00 70.55

Cefamandole nafate is a formate ester prodrug form of the cephalosporin antibiotic cefamandole (Item No. 18138).{43407} Cefamandole nafate inhibits the growth of E. cloacae, E. coli, K. pneumoniae, P. mirabilis, P. vulgaris, P. morganii, S. aureus, and S. pyogenes in vitro (MICs = 0.1-50 ?g/ml). In vivo, cefamanadole nafate protects against E. cloacae, E. coli, K. pneumoniae, P. mirabilis, P. vulgaris, P. morganii, S. aureus, and S. pyogenes infection in mice (ED50s = 0.3-334 mg/kg). Cefamandole (500 mg/kg) also protects against nephrotoxicity induced by the aminoglycoside antibiotic tobramycin (Item No. 14596) in rats.{43408}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • (6R,7R)-7-[[(2R)-2-(formyloxy)-2-phenylacetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, monosodium salt
  • Correlated keywords
    • 57268-80-1 Bergacef Cedol Cefam Cefamandole formate Cefiran Cemado Cemandil Cephamandole Fado Kefadol Kefandol Lampomandol Mandokef Mandol Mandolsan NSC299588 Neocefal O-Formylcefamandole Pavecef Enterobacter Escherichia Klebsiella Proteus Staphylococcus Streptococcus pro-drug
  • Product Overview:
    Cefamandole nafate is a formate ester prodrug form of the cephalosporin antibiotic cefamandole (Item No. 18138).{43407} Cefamandole nafate inhibits the growth of E. cloacae, E. coli, K. pneumoniae, P. mirabilis, P. vulgaris, P. morganii, S. aureus, and S. pyogenes in vitro (MICs = 0.1-50 ?g/ml). In vivo, cefamanadole nafate protects against E. cloacae, E. coli, K. pneumoniae, P. mirabilis, P. vulgaris, P. morganii, S. aureus, and S. pyogenes infection in mice (ED50s = 0.3-334 mg/kg). Cefamandole (500 mg/kg) also protects against nephrotoxicity induced by the aminoglycoside antibiotic tobramycin (Item No. 14596) in rats.{43408}

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