Cefamandole Nafate

Cefamandole Nafate

CAT N°: 23988
Price:

83.00 70.55

Cefamandole nafate is a formate ester prodrug form of the cephalosporin antibiotic cefamandole (Item No. 18138).{43407} Cefamandole nafate inhibits the growth of E. cloacae, E. coli, K. pneumoniae, P. mirabilis, P. vulgaris, P. morganii, S. aureus, and S. pyogenes in vitro (MICs = 0.1-50 ?g/ml). In vivo, cefamanadole nafate protects against E. cloacae, E. coli, K. pneumoniae, P. mirabilis, P. vulgaris, P. morganii, S. aureus, and S. pyogenes infection in mice (ED50s = 0.3-334 mg/kg). Cefamandole (500 mg/kg) also protects against nephrotoxicity induced by the aminoglycoside antibiotic tobramycin (Item No. 14596) in rats.{43408}

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