CAY10726

CAY10726

CAT N°: 23859
Price:

48.00 40.80

CAY10726 is an arylurea fatty acid.{40512} It decreases ATP production by 28% in MDA-MB-231 breast cancer cells when used at a concentration of 10 ?M. CAY10726 decreases proliferation and initiates apoptosis in MDA-MB-231 cells via depletion of the phospholipid cardiolipin and its precursor phosphatidylglycerol from the mitochondrial membrane. In vivo, CAY10726 (2.5-40 mg/kg) reduces tumor volume and increases tumor cell apoptosis in a mouse MDA-MB-231 breast cancer xenograft model in a dose-dependent manner.

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