Paromomycin (sulfate)

Paromomycin (sulfate)

CAT N°: 23634
Price:

From 92.00 78.20

Paromomycin is an aminoglycoside antibiotic that is effective against Gram-negative and Gram-positive bacteria (MICs = 0.08-3.9 µg/ml).{38389} It also has antiprotozoal properties and decreases the parasite burden of mice infected with the leishmanial strain L. tropica when administered at doses of 50 mg/kg and 15 mg/kg, through intramuscular or intralesional routes, respectively.{38388} Paromomycin binds to the tRNA decoding A site of the 16S ribosomal RNA in bacteria, inducing a conformational change that disrupts translation and inhibits protein synthesis.{38390}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • O-2,6-diamino-2,6-dideoxy-?-L-idopyranosyl-(1?3)-O-?-D-ribofuranosyl-(1?5)-O-[2-amino-2-deoxy-?-D-glucopyranosyl-(1?4)]-2-deoxy-D-streptamine, sulfate
  • Correlated keywords
    • 7542-37-2 1405-13-6 11048-06-9 14963-45-2 42438-81-3 51981-74-9 Aminosidin Aminoxidin FI-5853 FI5853 Farmiglucin Farminosidin Gabbroral Humagel Humatin Humycin Paramicina Pargonyl Paricina Sinosid 1600-Anti-biotic protozoal Leishmania aminosidine
  • Product Overview:
    Paromomycin is an aminoglycoside antibiotic that is effective against Gram-negative and Gram-positive bacteria (MICs = 0.08-3.9 µg/ml).{38389} It also has antiprotozoal properties and decreases the parasite burden of mice infected with the leishmanial strain L. tropica when administered at doses of 50 mg/kg and 15 mg/kg, through intramuscular or intralesional routes, respectively.{38388} Paromomycin binds to the tRNA decoding A site of the 16S ribosomal RNA in bacteria, inducing a conformational change that disrupts translation and inhibits protein synthesis.{38390}

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