Fluphenazine (hydro<wbr/>chloride)

Fluphenazine (hydrochloride)

CAT N°: 23555
Price:

49.00 41.65

Fluphenazine is a dopamine D1 and D2 receptor antagonist (Kis = 5 and 0.63 nM, respectively).{40356} It also binds to histamine H1, serotonin 5-HT2A, and 5-HT2B receptors (Kis = 45, 17, and 82 nM, respectively).{40357} It acts as an inverse agonist at H1 and 5-HT2A receptors.{40357,40358} Fluphenazine is a typical antipsychotic compound. It induces extrapyramidal symptoms in animal models, including monkeys.{40359} Formulations containing fluphenazine have been used in the management of psychotic disorders.

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