α-Zearalanol

α-Zearalanol

CAT N°: 23424
Price:

231.00 196.35

?-Zearalanol is an active metabolite formed by reduction of ?-zearalenol (Item No. 16549), an estrogen receptor antagonist.{27392} ?-Zearalanol inhibits [3H]estradiol binding to estrogen receptors (ERs) on calf uterus in a dose-dependent manner. Dietary ?-zearalanol (10 mg/kg per day) increases endometrial thickness, bone mineral density, and serum levels of alkaline phosphatase in ovariectomized rats.{35165} It also decreases sperm count and motility and serum levels of testosterone, follicle-stimulating hormone (FSH), and luteinizing hormone (LH) in male mice.{35167}

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