XMD16-5

XMD16-5

CAT N°: 23353
Price:

From 55.00 46.75

XMD16-5 is an inhibitor of tyrosine kinase non-receptor 2 (TNK2; IC50 = 0.38 µM), which contains mutations in certain cancer cells.{37179} It also decreases viability of Ba/F3 cells expressing the oncogenic TNK2 D163E and R806Q mutant proteins (IC50s = 16 and 77 nM, respectively) without affecting viability of parental cell lines up to a concentration of approximately 1 µM.

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 5,11-dihydro-2-[[4-(4-hydroxy-1-piperidinyl)phenyl]amino]-11-methyl-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one
  • Correlated keywords
    • XMD165 XMD-165 BaF3 TNK-2 D-163E R-806Q
  • Product Overview:
    XMD16-5 is an inhibitor of tyrosine kinase non-receptor 2 (TNK2; IC50 = 0.38 µM), which contains mutations in certain cancer cells.{37179} It also decreases viability of Ba/F3 cells expressing the oncogenic TNK2 D163E and R806Q mutant proteins (IC50s = 16 and 77 nM, respectively) without affecting viability of parental cell lines up to a concentration of approximately 1 µM.

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