Nerolidol

Nerolidol

CAT N°: 23182
Price:

From 48.00 40.80

Nerolidol is a sesquiterpene found in a variety of plants, including C. sativa, that has diverse biological activities, including antioxidant, anthelmintic, antinociceptive, and anti-inflammatory properties.{36924,43357,36925,36926,36927} It decreases superoxide dismutase (SOD) and catalase activity, reduces glutathione (GSH) levels, and increases malondialdehyde (MDA) levels in the brain when administered at a dose of 50 mg/kg in a rat model of Parkinson’s disease induced by rotenone (Item No. 13995).{36925} It also inhibits rotenone-induced increases in IL-1?, IL-6, and TNF-? in rat brain. Nerolidol (100, 200, and 400 mg/kg) reduces worm burden and egg production in a mouse model of schistosomiasis.{36926} It also decreases acetic acid-induced writhing and formalin-induced licking time in mice, indicating antinociceptive activity, and reduced carrageenan-induced paw edema when administered at doses of 300 and 400 mg/kg.{36927} Formulations containing nerolidol have been used as fragrance ingredients.

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 3,7,11-trimethyl-1,6,10-dodecatrien-3-ol
  • Correlated keywords
    • 35944-21-9 FCI 119b FCI119b Peruviol Cannabis anti-oxidant nociceptive antiinflammatory IL1? IL6 TNF? Nerodilol
  • Product Overview:
    Nerolidol is a sesquiterpene found in a variety of plants, including C. sativa, that has diverse biological activities, including antioxidant, anthelmintic, antinociceptive, and anti-inflammatory properties.{36924,43357,36925,36926,36927} It decreases superoxide dismutase (SOD) and catalase activity, reduces glutathione (GSH) levels, and increases malondialdehyde (MDA) levels in the brain when administered at a dose of 50 mg/kg in a rat model of Parkinson’s disease induced by rotenone (Item No. 13995).{36925} It also inhibits rotenone-induced increases in IL-1?, IL-6, and TNF-? in rat brain. Nerolidol (100, 200, and 400 mg/kg) reduces worm burden and egg production in a mouse model of schistosomiasis.{36926} It also decreases acetic acid-induced writhing and formalin-induced licking time in mice, indicating antinociceptive activity, and reduced carrageenan-induced paw edema when administered at doses of 300 and 400 mg/kg.{36927} Formulations containing nerolidol have been used as fragrance ingredients.

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