Alamethicin F50

Alamethicin F50

CAT N°: 23141
Price:

From 92.00 78.20

Alamethicin F50 is a peptaibol isolated from Trichoderma.{41167} It is a polymer of 20 amino acids that includes modified and non-proteinogenic amino acids.{41168} Alamethicin F50 is a mixture of 13 different peptides, with the most abundant designated as alamethicin F50/5. Alamethicin F50 forms voltage-dependent ion channels in lipid membranes and acts as a lytic agent.{41170,41169} It induces lysis of leukocytes (IC50 = 54 and 80 ?M for rat mast cells and mouse spleen lymphocytes, respectively) and exhibits antibacterial activity against a panel of 8 mollicutes (MICs = 1.56-12.5 ?M).

We also advise you