Avanafil

Avanafil

CAT N°: 23024
Price:

From 48.00 40.80

Avanafil is an orally bioavailable, potent, and competitive inhibitor of phosphodiesterase (PDE) 5 (IC50 = 2.2 nM).{40239} It is selective, with IC50 values of 630, >5,000, and >5,000 nM for PDE6, PDE1-4, and PDE7-11, respectively, in an enzyme assay. Avanafil potentiates penile tumescence in dogs in a dose-dependent manner. Formulations containing avanafil have been used to treat erectile dysfunction.{40271}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-2-[(2S)-2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2-pyrimidinylmethyl)-5-pyrimidinecarboxamide
  • Correlated keywords
    • 330785-17-6 647841-09-6 TA1790 ED Stendra Spedra
  • Product Overview:
    Avanafil is an orally bioavailable, potent, and competitive inhibitor of phosphodiesterase (PDE) 5 (IC50 = 2.2 nM).{40239} It is selective, with IC50 values of 630, >5,000, and >5,000 nM for PDE6, PDE1-4, and PDE7-11, respectively, in an enzyme assay. Avanafil potentiates penile tumescence in dogs in a dose-dependent manner. Formulations containing avanafil have been used to treat erectile dysfunction.{40271}

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