AR-7

AR-7

CAT N°: 22946
Price:

48.00 40.80

AR-7 is a retinoic acid receptor ? (RAR?) antagonist.{45302} In mouse fibroblasts, AR-7 (20 ?M) increases chaperone-mediated autophagy in an RAR?-dependent manner, increases LAMP-2A expression, and inhibits paraquat-induced decreases in cell viability. AR-7 is also selectively cytotoxic to HepG2 cells grown under hypoxic over normoxic conditions (IC50s = 10 and >1,000 ?M, respectively).{45303}

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