C16 Ceramide-d<sub>7</sub> (d18:1-d<sub>7</sub>/16:0)

C16 Ceramide-d7 (d18:1-d7/16:0)

CAT N°: 22787
Price:

548.00 465.80

C16 Ceramide-d7 is intended for use as an internal standard for the quantification of C16 ceramide (d18:1/16:0) by GC- or LC-MS. C16 Ceramide is a sphingolipid. It incorporates into the mitochondrial outer membrane and forms channels that increase its permeability.{58842} C16 Ceramide levels are increased by PPMP or MAPP in isolated human neutrophils and are correlated with an increase in apoptosis.{19145} It accumulates in the lungs of patients with cystic fibrosis compared with the lungs of patients with pulmonary hypertension.{58843} Plasma levels of C16 ceramide are also increased in patients with acute coronary syndrome, and an increased plasma ratio of C16 to C24:0 ceramide is associated with major adverse cardiac events.{58844} It is also increased in tumor tissue from patients with breast cancer and is associated with metastatic cancer.{58845}

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