24(S),25-epoxy Cholesterol
24(S),25-epoxy Cholesterol
24(S),25-epoxy Cholesterol is an oxysterol and the most abundant oxysterol in mouse ventral midbrain.{43943} It activates liver X receptors (LXRs)...
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From €48.00 €40.80
Epiblastin A is an ATP-competitive inhibitor of the casein kinase 1 (CK1) isoforms ?, ?, and ? (IC50s = 8.9, 0.5, and 4.7 ?M, respectively).{37345} It is selective for CK1?, CK1?, and CK1? at concentrations below 10 ?M, however, it also inhibits BRSK1, EEF2K, EGFR, MNK-2, and RIPK2 (IC50s = 24-45 ?M). Epiblastan A reduces immunoprecipitation of CK1?, CK1?, and CK1? from HCT116 cell lysates in a concentration-dependent manner. It induces reprogramming of mouse epiblast stem cells (mEpiSCs) into embryonic stem cells (ESCs) 8-fold more efficiently than triamterene (Item Nos. 21242 | 22486).
Territorial Availability: Available through Bertin Technologies only in France
| Size | 1 mg, 5 mg |
|---|---|
| Shipping | dry ice |
| CAS number | 16470-02-3 |
| Molecular formula | C12H10ClN7 |
| Smiles | NC1=NC2=NC(N)=NC(N)=C2N=C1C3=CC(Cl)=CC=C3 |
| Molecular weight | 287,7 |
| Custom code | 2903.99 |
| Formulation | A crystalline solid |
| Purity | ≥98% |
| UNSPSC code | 12352100 |
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Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.
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24(S),25-epoxy Cholesterol is an oxysterol and the most abundant oxysterol in mouse ventral midbrain.{43943} It activates liver X receptors (LXRs)...
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