Usnic Acid

Usnic Acid

CAT N°: 22585
Price:

From 37.00 31.45

Usnic acid is a lichen metabolite with antioxidant, anticancer, antifungal, antiprotozoal, and antimicrobial activities.{38108,38109,38110,38111,38112} Usnic acid (>50 mg/kg) reduces the number of indomethacin-induced gastric ulcers in rats through decreased lipid peroxidation and decreased myeloperoxidase activity.{38108} It is fungicidal against C. orthopsilosis and C. parapsilosis (IC80s = 7.8 and 15.6 ?g/ml, respectively) and bactericidal against seven vancomycin-resistant E. faecalis strains (MIC = 125 ?g/ml).{38109,38110} Usnic acid (25 mg/kg, injected intralesionally) reduces L. amazonensis parasite loads by 72.3% in footpads of infected mice.{38111} It also reduces growth of A2780, HeLa, MCF-7, SK-BR-3, HT-29, HCT116, HL-60, and Jurkat cancer cells in vitro (IC50s = 48.5-199 ?M).{38112}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 2,6-diacetyl-7,9-dihydroxy-8,9b-dimethyl-1,3(2H,9bH)-dibenzofurandione
  • Correlated keywords
    • 17669-01-1 21987-06-4 510-03-2 596-41-8 1946-70-9 11024-93-4 NSC8517 usnein usno anti-oxidant cancer fungal protozoal microbial MCF7 SKBR3 HT29 HCT116 HL60 (±)-usnic usniacin UA MPO candida enterococcus leishmania A-2780 HCT-116
  • Product Overview:
    Usnic acid is a lichen metabolite with antioxidant, anticancer, antifungal, antiprotozoal, and antimicrobial activities.{38108,38109,38110,38111,38112} Usnic acid (>50 mg/kg) reduces the number of indomethacin-induced gastric ulcers in rats through decreased lipid peroxidation and decreased myeloperoxidase activity.{38108} It is fungicidal against C. orthopsilosis and C. parapsilosis (IC80s = 7.8 and 15.6 ?g/ml, respectively) and bactericidal against seven vancomycin-resistant E. faecalis strains (MIC = 125 ?g/ml).{38109,38110} Usnic acid (25 mg/kg, injected intralesionally) reduces L. amazonensis parasite loads by 72.3% in footpads of infected mice.{38111} It also reduces growth of A2780, HeLa, MCF-7, SK-BR-3, HT-29, HCT116, HL-60, and Jurkat cancer cells in vitro (IC50s = 48.5-199 ?M).{38112}

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