AZD 3147

AZD 3147

CAT N°: 22474
Price:

From 48.00 40.80

AZD 3147 is an orally bioavailable dual inhibitor of mammalian target of rapamycin complex 1 (mTORC1) and mTORC2 (IC50s = 40.7 and 5.75 nM, respectively, in MDA-MB-468 cells).{55175} It is selective for mTOR over PI3K?, PI3K?, PI3K?, and PI3K? (IC50s = 1.51, 912, 5,495, 9,333, and 6,310 nM, respectively, in enzyme assays).

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